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Mentioned for the first time in a document about  commercial privilege granted by the Moldavian Prince ( Voievode) Alexander the Good  ( who ruled over Moldavia between 1400 and 1432) Iasi, known as “The Cultural Capital of Romania”, “The City of Great Loves”  or “The City on Seven Hills”, seemed always placed far from important places, further in Romania and much further in Europe. For a little while it was the residency of the Moldavia’s ruler and has missed by little the status of capital of Historical regions of Romania.

But all this historical and geographical misfortune was and is balanced out by the huge number of prominent people, artists, bookmen, savants or leaders who were born or have lived here. They have turned the small town into the city of great Romanian beginnings: cultural, historical, academic or artistic.

Alexandru cel Bun, Ştefan cel Mare, Vasile Lupu, Dimitrie Cantemir, Gheorghe Asachi, Alecu RussoA. D. XenopolSpiru Haret, Mihail Kogălnceanu, Alexandru Ioan Cuza, Mihai Eminescu, Ion Creangă, Vasile Alecsandri, Nicolae Iorga, Mihail Sadoveanu, Ionel Teodoreanu, George Emil Palade, Emil Racoviţă, Theodor Pallady, Corneliu Baba, Nicolae Tonitza, Matei Millo, Miluţă Gheorghiu or Sabin Bălaşa are some of the great figures who have influenced the city  that still claims the status of Cultural Capital of Romania.

Thus, all that fallows, happened for the first time, in the place that we call our dear Iasi:

1600 - Michael the Brave sanctified the Union of the Romanian Principalities

1638 - Vasile Lupu installed on the Three Hierarchs Church the first tower clock in Romania.

1646 - The Three Hierarchs typography published the first book of laws in Romania entitled „Carte românească de învăţătură de la pravilele împărăteşti şi de la alte giudeţe"

1671 - The Great Synagogue of Iaşi is founded ( first in the country)

1698- The first Romanian philosophical treaty written by Dmitrie Cantemir „Divanul sau Gâlceava înţeleptului cu lumea sau Giudeţul sufletului cu trupul”.

1714 - Dimitrie Cantemir is the first romanian member of a European academy,  The Berlin Academy.

1816 - takes place the first  theatrical representation in Romanian language, " Mirtil and Hloe " played in Constantin Ghica’s  house.

1833 - The first medical association is founded in Romania.

1834 - The first monument is built: The Obelisk with lions  in Copou park, monument sacred to the first Moldavian Constitution/ Organic Statute or Organic Regulation (Regulamentul Organic)

1834 –The first museum in Romania is founded: Natural History Museum of Iasi.

1839 –The first Romanian exhibition is organized: " Exhibition of  Flowers and exotic plants "

1848 -The first Romanian operetta representation took place: "Baba Harca " by Alexander

Flechtenmacher.

1848 - Iasi is the initiator of the Revolution of 1848, which has subsequently extended to the whole Romanian territory.

1856 - The first Botanical Garden opened in Romania.

1857 - Nulandt Bank is founded, the first mortgage bank in Romania.

1857 - First postage stamp entered the market, the famous "Bull Head".

1859 - The first University of Medicine was founded in Romania.

1860The first Romanian University, is inaugurated, currently the building of Grigore T. Popa University of  Medicine and Pharmacy

1862 - The first Romanian geology book is printed.  “The chalk from Repedea" by Gregory Cobalcescu.

1868 - Emil Racovita is born in Iasi, the first Romanian scientist who participated in an internationalscientific expedition.

1876 - The first Hebrew Theatre in the world opened in Iasi, founded by Abraham Goldfaden.

1887 - The first medical journal was printed. Medical and Surgical magazine.

1896 – The National Theatre "Vasile Alecsandri” is opened,  the first national theater in Romania.

1912 - George Emil Palade is born in Iasi, the only Romanian Nobel laureate (Physiology and Medicine, 1974).

 1918 - The first memorial house is opened: Ion Creanga's hut/hovel.

1976 - Theatrical Museum is opened, the first one of its kind in the country, in the house of the  Steward Alecsandri , former director of the theater that bears his name.